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Objective:To demonstrate the state of the art and trends on the global status of chronic disease management of patients with systemic lupus erythematosus (SLE) in recent 30 years.Methods:Literature relating to chronic disease management of patients with lupus from 1989 to 2018 was retrieved from Web of Science TM, using Mesh terms "lupus" and "management". CiteSpace was used to analyze countries/institutions, authors/cited authors, cited references and keywords. The information visualization analysis of centrality and counts was used to reveal countries/institutions, active authors, cited references, hot topics and frontiers. Results:A total of 3 328 papers were included, and a year-by-year increase of the number of publications were noticed. Most productive authors were from Europe, who were also open to communication and collaboration. Dr. M Petri is a representative figure in the area of lupus and antiphospholipid syndrome. She was involved in the composition of lupus classification and treatment guidelines, and played important roles in the arena of lupus treatment. Most productive countries/organizations were/from the United States, the United Kingdom, Spain, Italy, since European countries and organizations paid much attention to colaboration. The basis was focused on the treatment and management of lupus nephritis, the classification of lupus, the classification criteria of APS, and the usage as wells efficacy evaluation of belimumab in lupus. According to the time trend, the most popular key words were treatment, classification, antiphospholipid syndrome, disease activity, pregnancy, which could be categorized to 14 clusters. We could predicted that comprehensive evaluation including the clinical efficacy and safety of biological agents, as well as studies on quality of life and psychological state of lupus patients would become the main stream in this area. The research focus shifted from the diagnosis and treatment of lupus to the quality of life of patients.Conclusion:CiteSpace is used to collect the information of the literatures about chronic disease management of lupus. The results have shown that chronic disease management is still a hot topic. CiteSpace could help us to identify authors and institutions that are collaborative, as well as the research subjects that may lead the directions and future development.
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Objective To explore the efficacy and safety of endoscopic nasal vestibule cysts,lip gingival trench path nasal vestibule excision and low temperature plasma radiofrequency ablation under nasal endoscope in the treatment of nasal vestibule cyst.Methods From January 2013 to December 2017,ninety patients with nasal vestibule cyst admitted in Taiyuan Central Hospital were selected. According to different surgical methods,the patients were divided into nasal endoscope nasal vestibule cyst group( A group,26 cases),cleft lip gingival vestibule cyst excision group(B group,36 cases),low temperature plasma radiofrequency ablation group under nasal endoscopy( C group, 28 cases). The efficacy and safety of the three types of operation were compared. Results The operation time [(15.5 ± 3.6) min] and wound healing time [( 2. 3 ± 0. 9 ) d] in A group and the operation time [( 16. 3 ± 4.5)min],wound healing time[(2.1 ± 0.5)d] in C group were all significantly shorter than those in B group,the differences were statistically significant(t=5.268,4.698,5.624,4.267,all P<0.05).The amount of bleeding in C group[(9.3 ± 0.6)mL] was the least,followed by A group[(12.2 ± 1.7)mL],and the difference among the three groups was statistically significant(t=8.256,7.254,all P<0.05).The postoperative wound VAS score among the three groups was statistically significant(F=12.674,P<0.001),and the VAS score in C group[(1.6 ± 0.7)points]<A group[(3.2 ± 1.5)points]<B group[(4.9 ± 2.3)points],the differences among the three groups were statistically significant(t=4.256,3.998,2.989,all P<0.05).The degree of facial swelling in C group was mild(39.29% ) and moderate(60.71% ),the differences were statistically significant compared with those in A group and B group(χ2 =5.226,11.651,all P<0.05).The incidence rate of complications in C group (0.00% ) was significantly lower than that in A group(11.54% ) and B group (16.67% ),the difference was statistically significant ( χ2 =3.934, P < 0.05).Conclusion Compared with the endoscopic nasal vestibule cysts, lip gingival trench path nasal vestibule excision,the low temperature plasma ablation under nasal endoscopy in the treatment of nasal vestibular cyst has the best efficacy,it is safe,less painful,and not easy to relapse.
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Studies have found that depression is closely related to the hyperactivity of the hypothalamo–pituitary–adrenal (HPA) axis, which is manifested in increases in HPA axis-related hormones CRH, ACTH and CORT contents. Traditional Chinese medical acupuncture can down-regulate HPA axis levels to produce a marked antidepressant effect. However, at present there is no HPA axis mechanism analysis of the antidepressant effect of acupuncture. From two aspects: the relationship between depression and HPA axis, and clinical and animal mechanism studies of the antidepressant effect of acupuncture by regulating the HPA axis, an analysis has been made to provide a more powerful scientific basis and the idea of further in-depth study for clinical acupuncture treatment of depression.
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Human resources are the principle factor for survival and sustainable development of hospital libraries, the paper analyzes the status of human resources of hospital libraries in Shandong province where it could reveal the factors that effect human resources construction in hospital libraries, and then puts forward that hospital libraries should be under the management of information department,the leader of library should establish people-oriented concept for human resources construction and the developing trends of human resources construction should be established.